November 5, 2016

Abnormal Experiences of Life

Abnormal Experiences of Life

Many mental disorders have an initial onset in early adult life.  They can have a devastating effect on a person’s ability to function in the workplace and in social relationships and may lead to premature death through illness or suicide. The causes of most mental disorders are multifactorial, with contributions from genes and neurobiology, as well as from environmental circumstances and stress.  Understanding these processes holds the key to the development of more effective treatments.

Below is a list of researchers that we have funded in this area with the support of our wonderful donors. Click on the researcher’s name on the Our Researchers page to learn more about the researcher and their respective research project(s).


John Allen, Ph.D. – Imaging the “Affective” Anterior Cingulate in Depression
John Allen, Ph.D.- The Interaction of Candidate Genes and Frontal Brain Asymmetry in Risk for Depression
Cheryl Conrad, Ph.D. – Chronic Stress & Gender Effects on Prefrontal Cortex: Implications for Depression
Ronald Lukas, Ph.D. – Nicotonic Acetylcholine Receptors in Mental Health
Richard Lane, M.D., Ph.D. – Neural Basis of Vagal Tone Dysregulation in Depression
Francisco Moreno, M.D. – Association of Monoamine Systems Genes and Depression

Cancer and Depression

Karen Weihs, M.D. – Depression Care in Cancer Patients: Adapting a Primary Care Model

Bipolar Disorder

David Craig, Ph.D. – Genome-Wide Case-Control Association Study in Bipolar Using Pooled Genomic DNA


Nicholas Breitborde, M.D. – Multifamily Psychoeducation and Cognitive Remediation for First-Episode Psychosis
Amelia Gallitano-Mendel, M.D., Ph.D. & Matthew Huentelman, Ph.D. – Identification of Novel Schizophrenia Associations in the RF and ARC Genes
Jie Wu, M.D., Ph.D. – Nicotonic Receptors in the VTA and it’s Modulation of DA Neuron Function
Jie Wu, M.D., Ph.D.. – Hippocampal Gamma Oscillations in Nicotine- and Ketamine-Treated Rats

Post Traumatic Stress Disorder (PTSD)

Patricia Haynes, Ph.D. – Development of a Chronobiologically-Informed Intervention for Comorbid PTSD/MDD
Martha Kent, Ph.D. – Building Resilience: A Neurobiologically-Based Affective Intervention for PTSD
Patricia Haynes, Ph.D. & Michael Marks, Ph.D. – Development of Behavioral Sleep Medicine Intervention for Iraq Military Personnel

Substance Dependence

Edward Castaneda, Ph.D. – Presynaptic Mechanisms of Cross-Sensitization in Stimulant Drug Addiction

Emotions and Physical Health

Arthur Craig, Ph.D. – Homeostasis and Emotion
Mary Davis, Ph.D. – Emotional Resilience in FibromyalgiaL A study of web-based treatment
Richard Lane, M.D., Ph.D. & Cynthia Stonnington, M.D. – Deficits in Mental Representation of Emotion in Somatizing Patients
Nicole Roberts, Ph.D. – Emotional Responding in Psychogenic Nonepileptic Seizures